Methyldopa-induced syndrome of inappropriate antidiuretic hormone secretion and bone marrow granulomatosis

Y. Varkel; A. Braester; D. Nusem; T. Shkolnik

doi:10.1177/106002808802200911

Methyldopa-induced syndrome of inappropriate antidiuretic hormone secretion and bone marrow granulomatosis

Y. Varkel
, A. Braester
, D. Nusem
, T. Shkolnik

Western Galilee Medical Center of Nahariya

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A case of an elderly man who developed severe hyponatremia and bone marrow granulomatosis while taking methyldopa is described. The hyponatremia was found to be due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH). Bone marrow biopsy revealed granulomas. A MEDLINE search of the English literature was done, yielding only one previous report of methyldopa-induced bone marrow granulomatosis and no previous reports of methyldopa-induced SIADH.

Original language	English
Pages (from-to)	700-701
Number of pages	2
Journal	Drug Intelligence and Clinical Pharmacy
Volume	22
Issue number	9
DOIs	https://doi.org/10.1177/106002808802200911
State	Published - Sep 1988
Externally published	Yes

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abstract = "A case of an elderly man who developed severe hyponatremia and bone marrow granulomatosis while taking methyldopa is described. The hyponatremia was found to be due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH). Bone marrow biopsy revealed granulomas. A MEDLINE search of the English literature was done, yielding only one previous report of methyldopa-induced bone marrow granulomatosis and no previous reports of methyldopa-induced SIADH.",

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AB - A case of an elderly man who developed severe hyponatremia and bone marrow granulomatosis while taking methyldopa is described. The hyponatremia was found to be due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH). Bone marrow biopsy revealed granulomas. A MEDLINE search of the English literature was done, yielding only one previous report of methyldopa-induced bone marrow granulomatosis and no previous reports of methyldopa-induced SIADH.

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Methyldopa-induced syndrome of inappropriate antidiuretic hormone secretion and bone marrow granulomatosis

Abstract

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