Method and apparatus for predicting protein structure

Eran Eyal; Milana Frenkel-Morgenstern; Shmuel Pietrokovski; Vladimir Sobolev; Rachel Shakarov

Method and apparatus for predicting protein structure

Eran Eyal (Inventor), Milana Frenkel-Morgenstern (Inventor), Shmuel Pietrokovski (Inventor), Vladimir Sobolev (Inventor), Rachel Shakarov (Inventor)

Bar-Ilan University - Azrieli Faculty of Medicine

Yeda Research and Development Co Ltd

Research output: Patent

Abstract

A method of determining predicting putative contacting sites of a target protein is disclosed. The method uses a substitution matrix for calculating contact probabilities for pairs of columns in a sequence alignment containing the amino acid sequence of the target protein. The contact probabilities can also be used for predicting the three-dimensional structure of the protein. The putative contacts and/or three-dimensional structure typically correspond to the hydrophobic core of the target protein.

Original language	American English
Patent number	US20080215301A1
State	Published - 2008

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title = "Method and apparatus for predicting protein structure",

abstract = "A method of determining predicting putative contacting sites of a target protein is disclosed. The method uses a substitution matrix for calculating contact probabilities for pairs of columns in a sequence alignment containing the amino acid sequence of the target protein. The contact probabilities can also be used for predicting the three-dimensional structure of the protein. The putative contacts and/or three-dimensional structure typically correspond to the hydrophobic core of the target protein.",

author = "Eran Eyal and Milana Frenkel-Morgenstern and Shmuel Pietrokovski and Vladimir Sobolev and Rachel Shakarov",

year = "2008",

language = "American English",

publisher = "Yeda Research and Development Co Ltd",

type = "Patent",

note = "US20080215301A1",

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TY - PAT

T1 - Method and apparatus for predicting protein structure

AU - Eyal, Eran

AU - Frenkel-Morgenstern, Milana

AU - Pietrokovski, Shmuel

AU - Sobolev, Vladimir

AU - Shakarov, Rachel

PY - 2008

Y1 - 2008

N2 - A method of determining predicting putative contacting sites of a target protein is disclosed. The method uses a substitution matrix for calculating contact probabilities for pairs of columns in a sequence alignment containing the amino acid sequence of the target protein. The contact probabilities can also be used for predicting the three-dimensional structure of the protein. The putative contacts and/or three-dimensional structure typically correspond to the hydrophobic core of the target protein.

AB - A method of determining predicting putative contacting sites of a target protein is disclosed. The method uses a substitution matrix for calculating contact probabilities for pairs of columns in a sequence alignment containing the amino acid sequence of the target protein. The contact probabilities can also be used for predicting the three-dimensional structure of the protein. The putative contacts and/or three-dimensional structure typically correspond to the hydrophobic core of the target protein.

UR - https://patents.google.com/patent/US20080215301A1/en

M3 - Patent

M1 - US20080215301A1

PB - Yeda Research and Development Co Ltd

ER -

Method and apparatus for predicting protein structure

Abstract

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