Methamphetamine dependence is associated with neurocognitive impairment in the initial phases of abstinence

Ari D. Kalechstein, Thomas F. Newton, Michael Green

Research output: Contribution to journalArticlepeer-review

233 Scopus citations

Abstract

This study documented the association between neurocognitive impairment and methamphetamine dependence in a sample of 27 methamphetamine-dependent individuals who achieved 5 to 14 days of continuously monitored abstinence and in 18 control subjects. Methamphetamine-dependent individuals performed significantly worse than control subjects on neurocognitive measures sensitive to attention/psychomotor speed, on measures of verbal learning and memory, and on executive systems measures sensitive to fluency. These findings are the first to demonstrate that methamphetamine dependence is associated with impairments across a range of neurocognitive domains in a sample of users whose abstinence was continuously monitored with the use of urine screening.

Original languageEnglish
Pages (from-to)215-220
Number of pages6
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume15
Issue number2
DOIs
StatePublished - 2003

Fingerprint

Dive into the research topics of 'Methamphetamine dependence is associated with neurocognitive impairment in the initial phases of abstinence'. Together they form a unique fingerprint.

Cite this