Media for cultivation of animal cells: an overview

Avshalom Mizrahi, Arye Lazar

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations

Abstract

The increasing interest in products from animal cells has caused an extensive research effort towards development of media for cell cultivation. The basic components in the media used for cultivation of animal cells vary depending upon the characters of the cells and the cultivation method. Basic components consist of an energy source, nitrogen source, vitamins, fats and fatty soluble components, inorganic salts, nucleic acid precursors, antibiotics, oxygen, pH buffering systems, hormones, growth factors and serum. Extensive efforts are directed towards developing serum-free or chemically defined media. Among the serum substitutes is a long list of hormones and growth factors.

Original languageEnglish
Pages (from-to)199-214
Number of pages16
JournalCytotechnology
Volume1
Issue number3
DOIs
StatePublished - Jul 1988
Externally publishedYes

Keywords

  • animal cells
  • growth factors
  • mammalian cells
  • media
  • serum
  • tissue culture

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