Mechanistic Vistas of Trivalent Nitrogen Compound Reduction by Samarium Diiodide

Sandeepan Maity, Shmaryahu Hoz

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


In trivalent nitrogen compounds, the nitrogen lone pair is highly amenable to bind to samarium iodide prior to electron transfer. As SmI2 is more azaphilic than oxophilic, its affinity to the nitrogen lone pair is more pronounced in aza substrates than in the analogous carbonyl compounds. The impact of this binding is very large in terms of reaction rate and at the same time gives rise to unique mechanistic phenomena, which include unusual kinetic rate orders, catalysis by quantum dots, and remote functionalization. Even reduction of nitriles was found to be affected by this coordination to SmI2. This review focuses on the reduction mechanisms of three groups of compounds: imines, azobenzene, and nitriles.

Original languageEnglish
Pages (from-to)1103-1112
Number of pages10
JournalEuropean Journal of Organic Chemistry
Issue number7
StatePublished - 19 Feb 2021

Bibliographical note

Funding Information:
SH thanks the Israel Chemical science foundation for providing the funding to carry out the research work discussed in this review article.

Publisher Copyright:
© 2020 Wiley-VCH GmbH


  • Autocatalysis
  • Nitrogen coordination
  • Reaction mechanism
  • Reduction
  • Samarium iodide


Dive into the research topics of 'Mechanistic Vistas of Trivalent Nitrogen Compound Reduction by Samarium Diiodide'. Together they form a unique fingerprint.

Cite this