Measles outbreak associated with a preschool setting among partially vaccinated children in the Tel Aviv District, Israel, October 2023

Rivka Sheffer, Efrat Bucris, Ziva Amitai, Victoria Indenbaum, Yaniv Lustig, Michal Savion, Naama Nuss, Shepherd Roee Singer, Sharon Alroy Preis, Sharon Almagor, Eyal Leshem, Matanelle Salama

Research output: Contribution to journalArticlepeer-review

Abstract

In October 2023, the Tel Aviv District was notified of ten cases of measles. The outbreak initiated in a preschool with high vaccination coverage with one dose of MMR vaccine. Serological testing was available for eight patients (six children and two adults). Among the six children vaccinated with one dose of MMR vaccine, primary vaccine failure was demonstrated. Among the adults, secondary vaccine failure was confirmed. The outbreak was successfully contained due to a combination of factors, notably its occurrence within a population characterized by high vaccination coverage in Tel Aviv, during a period of restricted public interactions due to the prevailing state of war in the country. Despite challenging wartime conditions, effective prophylactic measures were promptly executed, encompassing a 2-dose MMR vaccination schedule for close contacts and the broader community of children in the TA district, successfully curbing the outbreak and preventing widespread infections.

Original languageEnglish
Pages (from-to)3153-3156
Number of pages4
JournalVaccine
Volume42
Issue number13
DOIs
StatePublished - 10 May 2024
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2024 The Authors

Keywords

  • Measles
  • Measles outbreak
  • Vaccine preventable diseases
  • Viral diseases

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