MCCB cognitive profile in Spanish first episode schizophrenia patients

  • R. Rodriguez-Jimenez
  • , J. L. Santos
  • , M. Dompablo
  • , J. Santabárbara
  • , A. I. Aparicio
  • , R. Olmos
  • , E. Jiménez-López
  • , E. Sánchez-Morla
  • , A. Lobo
  • , T. Palomo
  • , R. S. Kern
  • , M. F. Green
  • , K. H. Nuechterlein
  • , L. García-Fernández

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

The objective of the study was to examine the cognitive profile of Spanish patients with a first episode of schizophrenia (FESz) and to compare that to the profile of patients with a chronic schizophrenia (CSz) and non-psychiatric (NP) control subjects. The study included 106 FESz, 293 CSz, and 210 NP, assessed with the Spanish version of the MATRICS Consensus Cognitive Battery (MCCB). The MCCB cognitive profile in a Spanish sample of FESz was similar to the cognitive profile of CSz with some discrepancies in select domains. The scores of both patient samples were about 1–2 SD below the scores of non-psychiatric control subjects.

Original languageEnglish
Pages (from-to)88-92
Number of pages5
JournalSchizophrenia Research
Volume211
DOIs
StatePublished - Sep 2019
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2019 Elsevier B.V.

Funding

This research was supported in part by the by the Instituto de Salud Carlos III (grant PI16/00359; Fondo de Investigaciones Sanitarias/FEDER), by the European Development Regional Fund “A way to achieve Europe” (ERDF), by Madrid Regional Government (R&D activities in Biomedicine S2017/BMD-3740 (AGES-CM 2-CM)) and Structural Funds of the European Union. Instituto de Salud Carlos III (grant PI16/00359 ; Fondo de Investigaciones Sanitarias/ FEDER ), the European Development Regional Fund “A way to achieve Europe” ( ERDF ), Madrid Regional Government (R&D activities in Biomedicine S2017/BMD-3740 (AGES-CM 2-CM) ) and Structural Funds of the European Union , and the Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM) of the Instituto de Salud Carlos III.

FundersFunder number
Fondo de Investigaciones Sanitarias
Madrid Regional Government
European Commission
Federación Española de Enfermedades Raras
Instituto de Salud Carlos IIIPI16/00359
Centro de Investigación Biomédica en Red de Salud Mental
European Regional Development Fund

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

    Keywords

    • Cognition
    • First episode
    • MATRICS
    • MCCB
    • Schizophrenia

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