Abstract
We report a new method for multistep peptide synthesis on polymeric nanoparticles of differing sizes. Polymeric nanoparticles were functionalized via their temporary embedment into a magnetic inorganic matrix that allows multistep peptide synthesis. The matrix is removed at the end of the process for obtaining nanoparticles functionalized with peptides. The matrix-assisted synthesis on nanoparticles was proved by generating various biologically relevant peptides.
| Original language | English |
|---|---|
| Pages (from-to) | 675-679 |
| Number of pages | 5 |
| Journal | Journal of Peptide Science |
| Volume | 20 |
| Issue number | 9 |
| DOIs | |
| State | Published - Sep 2014 |
Keywords
- embedded nanoparticle
- magnetic matrix
- nanoparticle
- peptide
- solid phase peptide synthesis