Maternal serum creatine kinase: A possible predictor of tubal pregnancy

Ofer Lavie, Uziel Beller, Menachem Neuman, Avraham Ben-Chetrit, Shoshana Gottcshalk-Sabag, Yoram Z. Diamant

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55 Scopus citations


Tubal pregnancy remains a clinical challenge in spite of improvements in diagnostic tests and procedures. In a prospective study we evaluated the role of the serum creatine kinase as a possible marker for tubal pregnancy. Three groups of 17 patients each were included in the study: group A, documented tubal pregnancy; group B, spontaneous abortion; and group C, normal pregnancy. Serum was tested for creatine kinase in all of the patients. Creatine kinase level was >45 IU/L in all patients with tubal pregnancy, significantly higher than the level in patients in either of the two other groups (p < 0.0001). We conclude that a high serum creatine kinase level can be an important diagnostic test in the evaluation of a suspected tubal pregnancy.

Original languageEnglish
Pages (from-to)1149-1150
Number of pages2
JournalAmerican Journal of Obstetrics and Gynecology
Issue number5
StatePublished - Nov 1993
Externally publishedYes


  • Tubal pregnancy
  • creatine kinase
  • ectopic pregnancy


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