Managing thrombophilia during pregnancy

Thrombophilia is an inherited or acquired predisposition detected by a set of laboratory tests, which increases the risk for venous thromboembolism or pregnancy complications, as will be discussed. Thrombophilia, as with all other risk factors, should be looked for and modulated according to clinical presentation and risk stratification. Many articles have been written on thrombophilia and pregnancy, but this comprehensive article will focus on the issue from a unique perspective of each thrombophilia separately. This article will elaborate on the main types of thrombophilia and will suggest tools to the treating physician for dealing with thrombophilia during pregnancy. This article is the result of a search of the English literature on PubMed using thrombophilia, pregnancy, complications and thrombosis as keywords.