Mal de Meleda keratoderma with pseudoainhum

R. Bergman, O. Bitterman-Deutsch, M. Fartasch, R. Gershoni-Baruch, R. Friedman-Birnbaum

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42 Scopus citations


Pseudoainhum is an infrequent complication in the autosomal-recessive keratodermas. We describe two related families in which the diagnosis of mal de Meleda keratoderma has been confirmed by mode of inheritance and ultrastructural findings. One family member, a 9-year-old girl, developed pseudoainhum which threatened the viability of her little fingers. This responded to treatment with etretinate. The treatment dilemma posed by keratoderma-induced pseudoainhum in children, i.e. the concern over the possible skeletal toxic effects of long-term etretinate treatment vs. the risks and outcome of surgery, is discussed.

Original languageEnglish
Pages (from-to)207-212
Number of pages6
JournalBritish Journal of Dermatology
Issue number2
StatePublished - 1993
Externally publishedYes


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