TY - JOUR
T1 - Mal de Meleda keratoderma with pseudoainhum
AU - Bergman, R.
AU - Bitterman-Deutsch, O.
AU - Fartasch, M.
AU - Gershoni-Baruch, R.
AU - Friedman-Birnbaum, R.
PY - 1993/2
Y1 - 1993/2
N2 - Pseudoainhum is an infrequent complication in the autosomal-recessive keratodermas. We describe two related families in which the diagnosis of mal de Meleda keratoderma has been confirmed by mode of inheritance and ultrastructural findings. One family member, a 9-year-old girl, developed pseudoainhum which threatened the viability of her little fingers. This responded to treatment with etretinate. The treatment dilemma posed by keratoderma-induced pseudoainhum in children, i.e. the concern over the possible skeletal toxic effects of long-term etretinate treatment vs. the risks and outcome of surgery, is discussed.
AB - Pseudoainhum is an infrequent complication in the autosomal-recessive keratodermas. We describe two related families in which the diagnosis of mal de Meleda keratoderma has been confirmed by mode of inheritance and ultrastructural findings. One family member, a 9-year-old girl, developed pseudoainhum which threatened the viability of her little fingers. This responded to treatment with etretinate. The treatment dilemma posed by keratoderma-induced pseudoainhum in children, i.e. the concern over the possible skeletal toxic effects of long-term etretinate treatment vs. the risks and outcome of surgery, is discussed.
UR - http://www.scopus.com/inward/record.url?scp=0027459064&partnerID=8YFLogxK
U2 - 10.1111/j.1365-2133.1993.tb15153.x
DO - 10.1111/j.1365-2133.1993.tb15153.x
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C2 - 8457455
AN - SCOPUS:0027459064
SN - 0007-0963
VL - 128
SP - 207
EP - 212
JO - British Journal of Dermatology
JF - British Journal of Dermatology
IS - 2
ER -