Making the hospital a safer place by sonochemical coating of all its textiles with antibacterial nanoparticles

Ilana Perelshtein, Anat Lipovsky, Nina Perkas, Tzanko Tzanov, M. Arguirova, M. Leseva, Aharon Gedanken

Research output: Contribution to journalArticlepeer-review

55 Scopus citations


The ability to scale-up the sonochemical coating of medical textiles with antibacterial nanoparticles is demonstrated in the current paper. A roll-to-roll pilot installation to coat textiles was built taking into consideration the requirements of the sonochemical process. A long-run experiment was conducted in which 2500 m of fabric were coated with antibacterial ZnO nanoparticles (NPs). The metal oxide NPs were deposited from an ethanol:water solution. In this continuous process a uniform concentration of coated NPs over the length/width of the fabric was achieved. The antibacterial efficiency of the sono-chemically-coated textiles was validated in a hospital environment by a reduction in the occurrence of nosocomial infections. NP-coated bed sheets, patient gowns, pillow cover, and bed covers were used by 21 patients. For comparison 16 patients used regular textiles. The clinical data indicated the reduced occurrence of hospital-acquired infections when using the metal oxide NP-coated textiles. In order to reduce the cost of the coating process and considering safety issues during manufacturing, the solvent (ethanol:water) (9:1 v:v) used for the long-run experiment, was replaced by water. Although lesser amounts of ZnO NPs were deposited on the fabric in the water-based process the antibacterial activity of the textiles was preserved due to the smaller size of the particles.

Original languageEnglish
Pages (from-to)82-88
Number of pages7
JournalUltrasonics Sonochemistry
Issue number1
StatePublished - Jul 2015

Bibliographical note

Publisher Copyright:
© 2015 Elsevier B.V. All rights reserved.


  • Antibacterial textiles
  • Coating ZnO
  • CuO
  • Scale-up
  • Sonochemistry


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