Magnetic and Gold Nanoparticles Optimized for Cancer Treatment via Cell Hitchhiking

M. N. Yakovtseva; O. Betzer; A. V. Lunin; E. N. Mochalova; M. Beiderman; M. Motiei; S. D. Zvereva; O. B. Proushinskaya; T. Sadan; R. Popovtzer; M. P. Nikitin

doi:10.1109/ICLO48556.2020.9285858

Magnetic and Gold Nanoparticles Optimized for Cancer Treatment via Cell Hitchhiking

M. N. Yakovtseva, O. Betzer, A. V. Lunin, E. N. Mochalova, M. Beiderman, M. Motiei, S. D. Zvereva, O. B. Proushinskaya, T. Sadan, R. Popovtzer, M. P. Nikitin

Moscow Institute of Physics and Technology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

To date, targeting cancer cells by nanoparticles has been limited due to physical and biological obstructions, including the mononuclear phagocyte system. A novel approach for prolongation of nanoparticle circulation is cellular 'hitchhiking', or use of cells as vehicles to increase co-delivery of cancer therapeutics and particles to affected tissue. In this work, we studied the main characteristics of nanoagents based on magnetic and gold particles, to ensure optimal physicochemical characteristics. The developed agents hold promise to overcome the challenges that still hinder effective drug delivery for treatment of such complex diseases as cancer.

Original language	English
Title of host publication	Proceedings - International Conference Laser Optics 2020, ICLO 2020
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9781728152332
DOIs	https://doi.org/10.1109/ICLO48556.2020.9285858
State	Published - 2 Nov 2020
Externally published	Yes
Event	2020 International Conference Laser Optics, ICLO 2020 - St. Petersburg, Russian Federation Duration: 2 Nov 2020 → 6 Nov 2020

Publication series

Name	Proceedings - International Conference Laser Optics 2020, ICLO 2020

Conference

Conference	2020 International Conference Laser Optics, ICLO 2020
Country/Territory	Russian Federation
City	St. Petersburg
Period	2/11/20 → 6/11/20

Bibliographical note

Publisher Copyright:
© 2020 IEEE.

Keywords

Cellular hitchhiking
cancer therapy
magnetic gold hybrid nanoparticles
targeted drug delivery

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1109/ICLO48556.2020.9285858

Cite this

Yakovtseva, M. N., Betzer, O., Lunin, A. V., Mochalova, E. N., Beiderman, M., Motiei, M., Zvereva, S. D., Proushinskaya, O. B., Sadan, T., Popovtzer, R., & Nikitin, M. P. (2020). Magnetic and Gold Nanoparticles Optimized for Cancer Treatment via Cell Hitchhiking. In Proceedings - International Conference Laser Optics 2020, ICLO 2020 Article 9285858 (Proceedings - International Conference Laser Optics 2020, ICLO 2020). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ICLO48556.2020.9285858

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abstract = "To date, targeting cancer cells by nanoparticles has been limited due to physical and biological obstructions, including the mononuclear phagocyte system. A novel approach for prolongation of nanoparticle circulation is cellular 'hitchhiking', or use of cells as vehicles to increase co-delivery of cancer therapeutics and particles to affected tissue. In this work, we studied the main characteristics of nanoagents based on magnetic and gold particles, to ensure optimal physicochemical characteristics. The developed agents hold promise to overcome the challenges that still hinder effective drug delivery for treatment of such complex diseases as cancer.",

keywords = "Cellular hitchhiking, cancer therapy, magnetic gold hybrid nanoparticles, targeted drug delivery",

author = "Yakovtseva, {M. N.} and O. Betzer and Lunin, {A. V.} and Mochalova, {E. N.} and M. Beiderman and M. Motiei and Zvereva, {S. D.} and Proushinskaya, {O. B.} and T. Sadan and R. Popovtzer and Nikitin, {M. P.}",

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year = "2020",

month = nov,

day = "2",

doi = "10.1109/ICLO48556.2020.9285858",

language = "אנגלית",

series = "Proceedings - International Conference Laser Optics 2020, ICLO 2020",

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Yakovtseva, MN, Betzer, O, Lunin, AV, Mochalova, EN, Beiderman, M, Motiei, M, Zvereva, SD, Proushinskaya, OB, Sadan, T, Popovtzer, R & Nikitin, MP 2020, Magnetic and Gold Nanoparticles Optimized for Cancer Treatment via Cell Hitchhiking. in Proceedings - International Conference Laser Optics 2020, ICLO 2020., 9285858, Proceedings - International Conference Laser Optics 2020, ICLO 2020, Institute of Electrical and Electronics Engineers Inc., 2020 International Conference Laser Optics, ICLO 2020, St. Petersburg, Russian Federation, 2/11/20. https://doi.org/10.1109/ICLO48556.2020.9285858

Magnetic and Gold Nanoparticles Optimized for Cancer Treatment via Cell Hitchhiking. / Yakovtseva, M. N.; Betzer, O.; Lunin, A. V. et al.
Proceedings - International Conference Laser Optics 2020, ICLO 2020. Institute of Electrical and Electronics Engineers Inc., 2020. 9285858 (Proceedings - International Conference Laser Optics 2020, ICLO 2020).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AB - To date, targeting cancer cells by nanoparticles has been limited due to physical and biological obstructions, including the mononuclear phagocyte system. A novel approach for prolongation of nanoparticle circulation is cellular 'hitchhiking', or use of cells as vehicles to increase co-delivery of cancer therapeutics and particles to affected tissue. In this work, we studied the main characteristics of nanoagents based on magnetic and gold particles, to ensure optimal physicochemical characteristics. The developed agents hold promise to overcome the challenges that still hinder effective drug delivery for treatment of such complex diseases as cancer.

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Yakovtseva MN, Betzer O, Lunin AV, Mochalova EN, Beiderman M, Motiei M et al. Magnetic and Gold Nanoparticles Optimized for Cancer Treatment via Cell Hitchhiking. In Proceedings - International Conference Laser Optics 2020, ICLO 2020. Institute of Electrical and Electronics Engineers Inc. 2020. 9285858. (Proceedings - International Conference Laser Optics 2020, ICLO 2020). doi: 10.1109/ICLO48556.2020.9285858

Magnetic and Gold Nanoparticles Optimized for Cancer Treatment via Cell Hitchhiking

Abstract

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Bibliographical note

Keywords

UN SDGs

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