Low serum triiodothyronine and reverse triiodothyronine concentrations in patients with prolonged coma

J. Sack, L. Sazbon, S. Melmed, B. Lunenfeld, T. Najenson

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    3 Scopus citations

    Abstract

    We studied 10 patients (7 men and 3 women) hospitalized for prolonged coma (range, 61 to 1,320 days). The mean serum TBG and TSH concentrations were within the normal range for adults. However, the mean T 3 concentration was significantly lower than normal. The mean rT 3 concentration was not significantly different from normal. After TRF administration, there was a significant rise in mean serum TSH concentration, from 5.2 ± 0.6 to 11.3 ± 1.3 μunits/ml at 30 min. The rises in mean serum T 4 and rT 3 concentrations (to 10.6 ± 1.5 μg/dl and 22 ± 6 ng/dl, respectively) were not significant. However, there was a significant rise in mean serum T 3 concentration, from 81 ± 13 to 146 ± 18 ng/dl 120 min after TRF injection.

    Original languageEnglish
    Pages (from-to)402-403
    Number of pages2
    JournalIsrael Journal of Medical Sciences
    Volume16
    Issue number5
    StatePublished - May 1980

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