Low power visible light and hydrogen peroxide change intracellular calcium concentration in cardiac cells

Ronit Lavi, Asher Sheinberg, Harry Friedmann, Rachel Lubart

Research output: Contribution to journalConference articlepeer-review

Abstract

The free intracellular Ca2+ concentration changes in cardiac myocytes were compared after visible light irradiation and upon exposure to low concentration H2O2. Illuminating low energy doses (6 J/cm2) of visible light, or adding low concentration of H2O2 (35 μM) to cardiac cells resulted in elevated oscillations of [Ca2+]i that lasted for 200 min. Contraction of heart cells was also observed in parallel to calcium elevation. H2O2 mimicked the influence of light on [Ca2+]i, as well as on the biostimulatory effects.

Original languageEnglish
Pages (from-to)36-44
Number of pages9
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume3569
StatePublished - 1999
EventProceedings of the 1998 Effects of Low-Power Light on Biologigal Systems IV - Stockholm, SWE
Duration: 8 Sep 19989 Sep 1998

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