TY - JOUR
T1 - Long-range correlation measures for quantifying patchiness
T2 - Deviations from uniform power-law scaling in genomic DNA
AU - Viswanathan, G. M.
AU - Buldyrev, S. V.
AU - Havlin, S.
AU - Stanley, H. E.
PY - 1998/1/2
Y1 - 1998/1/2
N2 - We introduce and develop new techniques to quantify DNA patchiness, and characteristics of their mosaic structure. These techniques, which involve calculating two functions, α(ℓ) and β(ℓ), measure correlation exponents at length scale ℓ and detect distinct characteristic patch sizes embedded in scale invariant patch size distributions. Using these methods, it is possible to address a number of issues relating to the mosaic structure of genomic DNA. We find several distinct characteristic patch sizes in yeast, human, and prokaryotic sequences. We also find that the distinct patch sizes in all 16 yeast chromosomes are similar.
AB - We introduce and develop new techniques to quantify DNA patchiness, and characteristics of their mosaic structure. These techniques, which involve calculating two functions, α(ℓ) and β(ℓ), measure correlation exponents at length scale ℓ and detect distinct characteristic patch sizes embedded in scale invariant patch size distributions. Using these methods, it is possible to address a number of issues relating to the mosaic structure of genomic DNA. We find several distinct characteristic patch sizes in yeast, human, and prokaryotic sequences. We also find that the distinct patch sizes in all 16 yeast chromosomes are similar.
KW - DNA
KW - Long-range correlations
UR - http://www.scopus.com/inward/record.url?scp=0347965028&partnerID=8YFLogxK
U2 - 10.1016/S0378-4371(97)00519-0
DO - 10.1016/S0378-4371(97)00519-0
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AN - SCOPUS:0347965028
SN - 0378-4371
VL - 249
SP - 581
EP - 586
JO - Physica A: Statistical Mechanics and its Applications
JF - Physica A: Statistical Mechanics and its Applications
IS - 1-4
ER -