Abstract
Liquid biopsy for microbiome analysis is an emerging field that aims to study the composition and dynamics of microbial communities by analyzing biological fluids such as blood, urine, or saliva. This noninvasive method offers a useful approach to understanding microbiome dynamics. It provides insights into different pathologies, enables unbiased pathogen detection through noninvasive sampling, and offers rapid turnaround times. Clinical applications of liquid biopsy are emerging for microbiome exploration, particularly in areas such as infectious disease management, cancer diagnostics, and personalized medicine for chronic bowel diseases. This review highlights the role of liquid biopsy in infection and microbiome exploration, potentially revolutionizing diagnostics and tailored medicine by enabling the real-time monitoring of microbial shifts.
| Original language | English |
|---|---|
| Pages (from-to) | 389-400 |
| Number of pages | 12 |
| Journal | Trends in Biotechnology |
| Volume | 44 |
| Issue number | 2 |
| Early online date | 18 Jun 2025 |
| DOIs | |
| State | Published - Feb 2026 |
| Externally published | Yes |
Bibliographical note
Publisher Copyright:© 2025 Elsevier Ltd
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- cell-free DNA
- chimeric RNA
- liquid biopsy
- microbiome
- pathogens
- sequencing
- vesicles
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