Liposomes for Modulating Wiskott-Aldrich Syndrome Protein

Research output: Contribution to journalArticlepeer-review


Embodiments of the invention relate to liposomes comprising: a lipid bilayer having an internal cavity; a therapeutic agent within the internal cavity configured to modify expression or degradation of WASp in a cell; and a targeting moiety external to the lipid bilayer configured to target an extracellular domain of a cell. Embodiments of the invention relate to methods of treatment of disease comprising administering the liposomes. Novel pharmaceutical compositions are also disclosed.
Original languageAmerican English
Pages (from-to)962-962
JournalUS Patent App. 10,
StatePublished - 28 Oct 2018


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