TY - JOUR
T1 - Length-of-Stay in the Emergency Department and In-Hospital Mortality
T2 - A Systematic Review and Meta-Analysis
AU - Lauque, Dominique
AU - Khalemsky, Anna
AU - Boudi, Zoubir
AU - Östlundh, Linda
AU - Xu, Chang
AU - Alsabri, Mohammed
AU - Onyeji, Churchill
AU - Cellini, Jacqueline
AU - Intas, Geroge
AU - Soni, Kapil Dev
AU - Junhasavasdikul, Detajin
AU - Cabello, Jose Javier Trujillano
AU - Rathlev, Niels K.
AU - Liu, Shan W.
AU - Camargo, Carlos A.
AU - Slagman, Anna
AU - Christ, Michael
AU - Singer, Adam J.
AU - Houze-Cerfon, Charles Henri
AU - Aburawi, Elhadi H.
AU - Tazarourte, Karim
AU - Kurland, Lisa
AU - Levy, Phillip D.
AU - Paxton, James H.
AU - Tsilimingras, Dionyssios
AU - Kumar, Vijaya Arun
AU - Schwartz, David G.
AU - Lang, Eddy
AU - Bates, David W.
AU - Savioli, Gabriele
AU - Grossman, Shamai A.
AU - Bellou, Abdelouahab
N1 - Publisher Copyright:
© 2022 by the authors.
PY - 2022/12/21
Y1 - 2022/12/21
N2 - The effect of emergency department (ED) length of stay (EDLOS) on in-hospital mortality (IHM) remains unclear. The aim of this systematic review and meta-analysis was to determine the association between EDLOS and IHM. We searched the PubMed, Medline, Embase, Web of Science, Cochrane Controlled Register of Trials, CINAHL, PsycInfo, and Scopus databases from their inception until 14–15 January 2022. We included studies reporting the association between EDLOS and IHM. A total of 11,337 references were identified, and 52 studies (total of 1,718,518 ED patients) were included in the systematic review and 33 in the meta-analysis. A statistically significant association between EDLOS and IHM was observed for EDLOS over 24 h in patients admitted to an intensive care unit (ICU) (OR = 1.396, 95% confidence interval [CI]: 1.147 to 1.701; p < 0.001, I2 = 0%) and for low EDLOS in non-ICU-admitted patients (OR = 0.583, 95% CI: 0.453 to 0.745; p < 0.001, I2 = 0%). No associations were detected for the other cut-offs. Our findings suggest that there is an association between IHM low EDLOS and EDLOS exceeding 24 h and IHM. Long stays in the ED should not be allowed and special attention should be given to patients admitted after a short stay in the ED.
AB - The effect of emergency department (ED) length of stay (EDLOS) on in-hospital mortality (IHM) remains unclear. The aim of this systematic review and meta-analysis was to determine the association between EDLOS and IHM. We searched the PubMed, Medline, Embase, Web of Science, Cochrane Controlled Register of Trials, CINAHL, PsycInfo, and Scopus databases from their inception until 14–15 January 2022. We included studies reporting the association between EDLOS and IHM. A total of 11,337 references were identified, and 52 studies (total of 1,718,518 ED patients) were included in the systematic review and 33 in the meta-analysis. A statistically significant association between EDLOS and IHM was observed for EDLOS over 24 h in patients admitted to an intensive care unit (ICU) (OR = 1.396, 95% confidence interval [CI]: 1.147 to 1.701; p < 0.001, I2 = 0%) and for low EDLOS in non-ICU-admitted patients (OR = 0.583, 95% CI: 0.453 to 0.745; p < 0.001, I2 = 0%). No associations were detected for the other cut-offs. Our findings suggest that there is an association between IHM low EDLOS and EDLOS exceeding 24 h and IHM. Long stays in the ED should not be allowed and special attention should be given to patients admitted after a short stay in the ED.
KW - emergency department
KW - in-hospital mortality
KW - intensive care unit
KW - length-of-stay
KW - meta-analysis
KW - systematic review
UR - https://www.scopus.com/pages/publications/85145768603
U2 - 10.3390/jcm12010032
DO - 10.3390/jcm12010032
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C2 - 36614835
AN - SCOPUS:85145768603
SN - 2077-0383
VL - 12
JO - Journal of Clinical Medicine
JF - Journal of Clinical Medicine
IS - 1
M1 - 32
ER -