Legionella pneumophila and pneumocystis jirovecii coinfection in an infant treated with adrenocorticotropic hormone for infantile spasm: Case report and literature review

Nadira Musallam, Ellen Bamberger, Isaac Srugo, Husein Dabbah, Daniel Glikman, Zeev Zonis, Aharon Kessel, Jacob Genizi

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations

Abstract

We describe an 8-month-old infant with infantile spasms treated with adrenocorticotropic hormone (ACTH) who presented with fatal Legionella pneumophila and Pneumocystis jirovecii infection. Emphasis is placed on the ensuing immunosuppression and infectious sequelae of ACTH therapy. Given that ACTH therapy may increase the risk of fatal infection, patients undergoing such treatment should be closely monitored, with particular attention paid to the functioning of the immune system.

Original languageEnglish
Pages (from-to)240-242
Number of pages3
JournalJournal of Child Neurology
Volume29
Issue number2
DOIs
StatePublished - Feb 2014

Keywords

  • Legionella pneumophila
  • Pneumocystis jirovecii
  • adrenocorticotropic hormone
  • immunosuppression
  • infantile spasms

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