Left Ventricular Assist Device as Destination Therapy: a State of the Science and Art of Long-Term Mechanical Circulatory Support

Thomas C. Hanff, Edo Y. Birati

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations

Abstract

Purpose of Review: The purpose of this review is to synthesize and summarize recent developments in the care of patients with end-stage heart failure being managed with a left ventricular assist device (LVAD) as destination therapy. Recent Findings: Although the survival of patients treated with LVAD continues to improve, the rates of LVAD-associated complication, such as right ventricular failure, bleeding complications, and major infection, remain high, and management of these patients remains challenging. Summary: The durability and hemocompatibility of LVAD support have greatly increased in recent years as a result of new technologies and novel management strategies. Challenges remain in the comprehensive care of patients with destination therapy LVADs, including management of comorbidities and optimizing patient function and quality of life.

Original languageEnglish
Pages (from-to)168-179
Number of pages12
JournalCurrent Heart Failure Reports
Volume16
Issue number5
DOIs
StatePublished - 1 Oct 2019
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2019, Springer Science+Business Media, LLC, part of Springer Nature.

Funding

Dr. Hanff is supported by an NIH Cardiopulmonary Epidemiology T32 Training Grant (HL-007891). Dr. Birati receives paid consulting fees from American Regent Inc.

FundersFunder number
NIH Cardiopulmonary Epidemiology T32 TrainingHL-007891

    Keywords

    • Adverse events
    • Destination therapy
    • LVAD
    • Long-term
    • Management

    Fingerprint

    Dive into the research topics of 'Left Ventricular Assist Device as Destination Therapy: a State of the Science and Art of Long-Term Mechanical Circulatory Support'. Together they form a unique fingerprint.

    Cite this