Abstract
Large scale production of human lymphoblastoid (Namalva) interferon (IF) is described. Cell propagation, in up to 50 1 culture volume, was carried out in a low cost medium by a semi-continuous cultivation method. IF was induced by Sendai virus, testing two induction methods. The yield of crude IF varied in the range of 12 - 100 × 103 IF units.ml-1. A weekly production output of 1 - 5 × 108 units crude IF was obtained.
Original language | English |
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Pages (from-to) | 267-271 |
Number of pages | 5 |
Journal | Biotechnology Letters |
Volume | 2 |
Issue number | 6 |
DOIs | |
State | Published - Jun 1980 |
Externally published | Yes |