Laponite-based nanomaterials for biomedical applications: A review

Sabya S. Das, Neelam, Kashif Hussain, Sima Singh, Afzal Hussain, Abdul Faruk, Mike Tebyetekerwa

Research output: Contribution to journalArticlepeer-review

63 Scopus citations

Abstract

Laponite based nanomaterials (LBNMs) are highly diverse regarding their mechanical, chemical, and structural properties, coupled with shape, size, mass, biodegradability and biocompatibility. These ubiquitous properties of LBNMs make them appropriate materials for extensive applications. These have enormous potential for effective and targeted drug delivery comprised of numerous biodegradable materials which results in enhanced bioavailability. Moreover, the clay material has been explored in tissue engineering and bioimaging for the diagnosis and treatment of various diseases. The material has been profoundly explored for minimized toxicity of nanomedicines. The present review compiled relevant and informative data to focus on the interactions of laponite nanoparticles and application in drug delivery, tissue engineering, imaging, cell adhesion and proliferation, and in biosensors. Eventually, concise conclusions are drawn concerning biomedical applications and identification of new promising research directions.

Original languageEnglish
Pages (from-to)424-433
Number of pages10
JournalCurrent Pharmaceutical Design
Volume25
Issue number4
DOIs
StatePublished - 2019
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2019 Bentham Science Publishers.

Keywords

  • Applications
  • Composition and characteristics
  • Drug delivery and biosensor
  • Laponite (lap)
  • Laponite-based nano-materials (lbnms)

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