TY - JOUR
T1 - Laponite-based nanomaterials for biomedical applications
T2 - A review
AU - Das, Sabya S.
AU - Neelam,
AU - Hussain, Kashif
AU - Singh, Sima
AU - Hussain, Afzal
AU - Faruk, Abdul
AU - Tebyetekerwa, Mike
N1 - Publisher Copyright:
© 2019 Bentham Science Publishers.
PY - 2019
Y1 - 2019
N2 - Laponite based nanomaterials (LBNMs) are highly diverse regarding their mechanical, chemical, and structural properties, coupled with shape, size, mass, biodegradability and biocompatibility. These ubiquitous properties of LBNMs make them appropriate materials for extensive applications. These have enormous potential for effective and targeted drug delivery comprised of numerous biodegradable materials which results in enhanced bioavailability. Moreover, the clay material has been explored in tissue engineering and bioimaging for the diagnosis and treatment of various diseases. The material has been profoundly explored for minimized toxicity of nanomedicines. The present review compiled relevant and informative data to focus on the interactions of laponite nanoparticles and application in drug delivery, tissue engineering, imaging, cell adhesion and proliferation, and in biosensors. Eventually, concise conclusions are drawn concerning biomedical applications and identification of new promising research directions.
AB - Laponite based nanomaterials (LBNMs) are highly diverse regarding their mechanical, chemical, and structural properties, coupled with shape, size, mass, biodegradability and biocompatibility. These ubiquitous properties of LBNMs make them appropriate materials for extensive applications. These have enormous potential for effective and targeted drug delivery comprised of numerous biodegradable materials which results in enhanced bioavailability. Moreover, the clay material has been explored in tissue engineering and bioimaging for the diagnosis and treatment of various diseases. The material has been profoundly explored for minimized toxicity of nanomedicines. The present review compiled relevant and informative data to focus on the interactions of laponite nanoparticles and application in drug delivery, tissue engineering, imaging, cell adhesion and proliferation, and in biosensors. Eventually, concise conclusions are drawn concerning biomedical applications and identification of new promising research directions.
KW - Applications
KW - Composition and characteristics
KW - Drug delivery and biosensor
KW - Laponite (lap)
KW - Laponite-based nano-materials (lbnms)
UR - http://www.scopus.com/inward/record.url?scp=85068487553&partnerID=8YFLogxK
U2 - 10.2174/1381612825666190402165845
DO - 10.2174/1381612825666190402165845
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C2 - 30947654
AN - SCOPUS:85068487553
SN - 1381-6128
VL - 25
SP - 424
EP - 433
JO - Current Pharmaceutical Design
JF - Current Pharmaceutical Design
IS - 4
ER -