Kohler disease: Diagnoses and assessment by bone scintigraphy

Jabour Khoury, Jacqueline Jerushalmi, Norman Loberant, Haim Shtarker, Daniela Militianu, Zohar Keidar

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Limping is a frequent occurrence in children and may be caused by various conditions, including trauma, inflammation, infection, and malignancy. Nontraumatic avascular necrosis of the tarsal bones should be included in the differential diagnosis. Accumulated data have supported the superiority of bone scans to radiography in the early diagnosis of avascular necrosis. Bone scintigraphy is a useful tool for investigating pain when symptoms, laboratory examinations, and radiography do not point to a specific diagnosis. In the early phase of disease, bone scans may demonstrate decreased tracer uptake (photopenic region), subsequently a hot area is seen during the reparative process. Although magnetic resonance imaging has important implications in the diagnosis of avascular necrosis, bone scintigraphy with its ready availability has a significant role as a primary tool in the evaluation of a limping child.

Original languageEnglish
Pages (from-to)179-181
Number of pages3
JournalClinical Nuclear Medicine
Issue number3
StatePublished - Mar 2007
Externally publishedYes


  • Avascular necrosis
  • Bone scintigraphy
  • MRI
  • Tarsal navicular


Dive into the research topics of 'Kohler disease: Diagnoses and assessment by bone scintigraphy'. Together they form a unique fingerprint.

Cite this