Isotope Labeling Study of Retinal Chromophore Fragmentation

Lihi Musbat, Maria Nihamkin, Shany Ytzhak, Amiram Hirshfeld, Noga Friedman, Jonathan M. Dilger, Mordechai Sheves, Yoni Toker

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Previous studies have shown that the gas-phase fragmentation of the retinal chromophore after S0-S1 photoexcitation results in a prominent fragment of mass 248 which cannot be explained by the cleavage of any single bond along the polyene chain. It was therefore theorized that the fragmentation mechanism involves a series of isomerizations and cyclization processes, and two mechanisms for these processes were suggested. Here we used isotope labeling MS-MS to provide conclusive support for the fragmentation mechanism suggested by Coughlan et al. (J. Phys. Chem. Lett. 2014, 5, 3195).

Original languageEnglish
Pages (from-to)2547-2549
Number of pages3
JournalJournal of Physical Chemistry A
Volume120
Issue number16
DOIs
StatePublished - 28 Apr 2016

Bibliographical note

Publisher Copyright:
© 2016 American Chemical Society.

Funding

This research was supported by GIF Research Grant No. I-2370-303.7/2014 and by the Israel Science Foundation.

FundersFunder number
German-Israeli Foundation for Scientific Research and DevelopmentI-2370-303.7/2014
Israel Science Foundation

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