Isolated polyhydramnios in the third trimester: is a gestational diabetes evaluation of value?*

Maya Frank Wolf, David Peleg, Talia Stahl-Rosenzweig, Yaffa Kurzweil, Yariv Yogev

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


We evaluated implications of testing for gestational diabetes mellitus (GDM) in pregnancies complicated by third trimester isolated polyhydramnios with previous negative diabetes screening test. In this retrospective cohort study of 104 pregnant women with polyhydramnios between 2005 and 2013, all had normal first trimester fasting glucose and normal glucose challenge test (GCT < 140 mg/dL). Late onset GDM was diagnosed in five women (4.8%) with isolated polyhydramnios, one abnormal value in the oral glucose tolerance test (OGTT) was identified in four additional women (3.8%). No significant differences were found in risk factors for GDM, mean second trimester GCT (117.5 vs. 107.2 mg/dL, p = 0.38) or fasting glucose values (82 vs. 86 mg/dL, p = 0.29) between women in the polyhydramnios group with and without late GDM diagnosis. Moreover, no significant difference was found in relation to the mode of delivery or birth weight between the studied groups (3437 ± 611 vs. 3331 ± 515 g, p = 0.63). Diagnosis of third trimester polyhydramnios was not associated with increased risk for GDM or neonatal complications.

Original languageEnglish
Pages (from-to)849-852
Number of pages4
JournalGynecological Endocrinology
Issue number11
StatePublished - 2 Nov 2017

Bibliographical note

Publisher Copyright:
© 2017 Informa UK Limited, trading as Taylor & Francis Group.


  • Delivery
  • gestational diabetes
  • neonatal outcome
  • polyhydramnios
  • third trimester


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