Is there any sense in antisense editing?

Yossef Neeman, Dvir Dahary, Erez Y. Levanon, Rotem Sorek, Eli Eisenberg

Research output: Contribution to journalShort surveypeer-review

39 Scopus citations


Several recent studies have hypothesized that sense-antisense RNA-transcript pairs create dsRNA duplexes that undergo extensive A-to-I RNA editing. We studied human and mouse genomic antisense regions and found that the editing level in these areas is negligible. This observation questions the scope of sense-antisense duplexes formation in-vivo, which is the basis for several proposed regulatory mechanisms.

Original languageEnglish
Pages (from-to)544-547
Number of pages4
JournalTrends in Genetics
Issue number10
StatePublished - Oct 2005
Externally publishedYes

Bibliographical note

Funding Information:
R.S. was supported by a fellowship from the Clore Israel Foundation. E.E. was supported by an Alon Fellowship at Tel Aviv University.


Dive into the research topics of 'Is there any sense in antisense editing?'. Together they form a unique fingerprint.

Cite this