Iryantherins, lignoflavonoids of novel structural types from the myristicaceae

Lucia M. Conserva, Massayoshi Yoshida, Otto R. Gottlieb, Juan C. Martinez V, Hugo E. Gottlieb

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


Iryanthera laevis, I. ulei and I. paraensis contain a series of novel lignoflavonoids the formation of which can be rationalized by the cinnamylation of the phloroglucinol type A-ring of a dihydrochalcone. The lignoid attachments of the flavonoid moieties consist of an arylvinylmethyl group in iryantherin-A, of 1,4-diaryl-2,3-dimethyl-n-butyl groups in iryantherins B and C and of 3-aryl-2-cinnamyl-n-propyl groups in iryantherins D and E. The construction of iryantherin-F requires oxidative addition of the vinyl unit of an iryantherin-A type compound to the A-ring of a second dihydrochalcone moiety.

Original languageEnglish
Pages (from-to)3911-3918
Number of pages8
Issue number12
StatePublished - 1990


  • I. paraensis
  • I. ulei
  • Iryanthera laevis
  • Myristicaceae
  • dihydrochalcones
  • iryantherins, phenol cinnamylation.
  • lignoflavonoids


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