Abstract
This study considered effects of timing and duration of iron deficiency (ID) on frontal EEG asymmetry in infancy. In healthy term Chinese infants, EEG was recorded at 9 months in three experimental conditions: baseline, peek-a-boo, and stranger approach. Eighty infants provided data for all conditions. Prenatal ID was defined as low cord ferritin or high ZPP/H. Postnatal ID was defined as ≥ two abnormal iron measures at 9 months. Study groups were pre- and postnatal ID, prenatal ID only, postnatal ID only, and not ID. GLM repeated measure analysis showed a main effect for iron group. The pre- and postnatal ID group had negative asymmetry scores, reflecting right frontal EEG asymmetry (mean±SE: -.18±.07) versus prenatal ID only (.00±.04), postnatal ID only (.03±.04), and not ID (.02±.04). Thus, ID at both birth and 9 months was associated with right frontal EEG asymmetry, a neural correlate of behavioral withdrawal and negative emotions.
Original language | English |
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Pages (from-to) | 462-470 |
Number of pages | 9 |
Journal | Developmental Psychobiology |
Volume | 58 |
Issue number | 4 |
DOIs | |
State | Published - 1 May 2016 |
Externally published | Yes |
Bibliographical note
Publisher Copyright:© 2016 Wiley Periodicals, Inc.
Funding
NIH Contract grant number: P01 HD039386 Contract grant sponsor: National Natural Science Foundation of China (NSFC) Contract grant number: 81273085
Funders | Funder number |
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National Institutes of Health | |
National Institute of Child Health and Human Development | P01HD039386 |
National Natural Science Foundation of China | 81273085 |
Keywords
- EEG
- Emotion
- Iron deficiency
- Pre- and postnatal