Iontophoresis: A non-invasive ocular drug delivery

Esther Eljarrat-Binstock, Abraham J. Domb

Research output: Contribution to journalReview articlepeer-review

171 Scopus citations

Abstract

Iontophoresis as a non-invasive technique for ocular drug delivery has been investigated for many years. This paper provides an overview of the approaches currently used in the development of the ocular iontophoretic device, the essential features of this procedure and the reported toxicity. This review focuses on the experimental results after transcorneal and transscleral iontophoresis of different drugs, emphasizing the current density applied and the treatment duration used by the investigators.

Original languageEnglish
Pages (from-to)479-489
Number of pages11
JournalJournal of Controlled Release
Volume110
Issue number3
DOIs
StatePublished - 21 Feb 2006
Externally publishedYes

Keywords

  • Eye
  • Hydrogel
  • Iontophoresis
  • Ocular delivery

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