Intravenous and regional paclitaxel formulations

Rajendra Pawar, Ariella Shikanov, Boris Vaisman, Abraham J. Domb

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations

Abstract

Paclitaxel has been proven to be effective against different types of cancer. A delivery system loaded with paclitaxel at tumor site should provide a high local concentration of the drug detrimental to malignant cells, which prevents the re-growth and metastasis of tumor. In this review, paclitaxel formulations for systemic and for intratumoral administration are discussed.

Original languageEnglish
Pages (from-to)397-402
Number of pages6
JournalCurrent Medicinal Chemistry
Volume11
Issue number4
DOIs
StatePublished - Feb 2004
Externally publishedYes

Keywords

  • Delivery systems
  • Formulations
  • Intratumoral delivery
  • Paclitaxel
  • Polymers

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