Intramolecular oxime olefin cycloadditions. Stereospecific formation of functionalized pyrrolidines.

Alfred Hassner; Rakesh Maurya; Eszter Mesko

doi:10.1016/s0040-4039(00)80746-7

Intramolecular oxime olefin cycloadditions. Stereospecific formation of functionalized pyrrolidines.

Alfred Hassner
, Rakesh Maurya
, Eszter Mesko

Department of Chemistry

Bar-Ilan University

Research output: Contribution to journal › Article › peer-review

64 Scopus citations

Abstract

Allylamines possessing a properly positioned aldoxime or ketoxime chain undergo thermally induced dipolar cycloaddition to bicylic isoxazolidines, with stereospecific introduction of three stereo centers. This provides an entry into stereospecifically functionalized pyrrolidines.

Original language	English
Pages (from-to)	5313-5316
Number of pages	4
Journal	Tetrahedron Letters
Volume	29
Issue number	41
DOIs	https://doi.org/10.1016/s0040-4039(00)80746-7
State	Published - 1988

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title = "Intramolecular oxime olefin cycloadditions. Stereospecific formation of functionalized pyrrolidines.",

abstract = "Allylamines possessing a properly positioned aldoxime or ketoxime chain undergo thermally induced dipolar cycloaddition to bicylic isoxazolidines, with stereospecific introduction of three stereo centers. This provides an entry into stereospecifically functionalized pyrrolidines.",

author = "Alfred Hassner and Rakesh Maurya and Eszter Mesko",

year = "1988",

doi = "10.1016/s0040-4039(00)80746-7",

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AU - Maurya, Rakesh

AU - Mesko, Eszter

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AB - Allylamines possessing a properly positioned aldoxime or ketoxime chain undergo thermally induced dipolar cycloaddition to bicylic isoxazolidines, with stereospecific introduction of three stereo centers. This provides an entry into stereospecifically functionalized pyrrolidines.

UR - https://www.scopus.com/pages/publications/0000722910

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 41

ER -

Intramolecular oxime olefin cycloadditions. Stereospecific formation of functionalized pyrrolidines.

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