Integrative Genomic Analysis Identifies Isoleucine and CodY as Regulators of Listeria monocytogenes Virulence

Keyphrases

• Leucine 100%
• Genome Analysis 100%
• Listeria Monocytogenes 100%
• Virulence 100%
• CodY 100%
• PrfA 66%
• Branched-chain Amino Acids 50%
• Metabolism 33%
• Metabolic Requirements 33%
• Metabolic Pathways 33%
• Adaptation 16%
• Catabolism 16%
• Arginine 16%
• Rhamnose 16%
• Regulatory Mechanism 16%
• Histidine 16%
• Purine 16%
• Mammalian Cells 16%
• Macrophage Cells 16%
• Glycerol 16%
• Amino Acid Content 16%
• Regulatory Genes 16%
• Knockout mutant 16%
• Gene Knockout 16%
• Genome-scale Metabolic Model 16%
• Intracellular Replication 16%
• Intracellular Bacterial Pathogens 16%
• Growth in Macrophages 16%
• De-novo Synthesis 16%
• Transcriptomic Data 16%
• Metabolomic Analysis 16%

Biochemistry, Genetics and Molecular Biology

• Metabolic Pathway 100%
• Amino Acids 100%
• Listeria monocytogenes 100%
• Genomics 100%
• Isoleucine 100%
• Infectious Agent 66%
• Macrophage 33%
• Glycerol 33%
• Gene Targeting 33%
• Catabolism 33%
• Gene Knockout 33%
• Histidine 33%
• Arginine 33%
• Transcriptome 33%
• Rhamnose 33%

Immunology and Microbiology

• Listeria monocytogenes 100%
• Amino Acid 100%
• Isoleucine 100%
• Infectious Disease 66%
• Infectious Agent 66%
• Infection 66%
• Macrophage 33%
• Transcriptome 33%
• Catabolism 33%
• Metabolism 33%
• Gene Targeting 33%
• Gene Knockout 33%
• Arginine 33%
• Replication 33%
• Histidine 33%
• Glycerol 33%