Integration of mouse phenome data resources

John M. Hancock; Niels C. Adams; Vassilis Aidinis; Andrew Blake; Judith A. Blake; Molly Bogue; Steve D.M. Brown; Elissa Chesler; Duncan Davidson; Christopher Duran; Janan T. Eppig; Valérie Gailus-Durner; Hilary Gates; Georgios V. Gkoutos; Simon Greenaway; Martin Hrabé De Angelis; George Kollias; Sophie Leblanc; Kirsty Lee; Christoph Lengger; Holger Maier; Ann Marie Mallon; Hiroshi Masuya; David G. Melvin; Werner Müller; Helen Parkinson; Glenn Proctor; Eli Reuveni; Paul Schofield; Aadya Shukla; Cynthia Smith; Tetsuro Toyoda; Laurent Vasseur; Shigeharu Wakana; Alison Walling; Jacqui White; Joe Wood; Michalis Zouberakis

doi:10.1007/s00335-007-9004-x

Integration of mouse phenome data resources

John M. Hancock, Niels C. Adams, Vassilis Aidinis, Andrew Blake, Judith A. Blake, Molly Bogue, Steve D.M. Brown, Elissa Chesler, Duncan Davidson, Christopher Duran, Janan T. Eppig, Valérie Gailus-Durner, Hilary Gates, Georgios V. Gkoutos, Simon Greenaway, Martin Hrabé De Angelis, George Kollias, Sophie Leblanc, Kirsty Lee, Christoph LenggerHolger Maier, Ann Marie Mallon, Hiroshi Masuya, David G. Melvin, Werner Müller, Helen Parkinson, Glenn Proctor, Eli Reuveni, Paul Schofield, Aadya Shukla, Cynthia Smith, Tetsuro Toyoda, Laurent Vasseur, Shigeharu Wakana, Alison Walling, Jacqui White, Joe Wood, Michalis Zouberakis

Research output: Contribution to journal › Article › peer-review

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Abstract

Understanding the functions encoded in the mouse genome will be central to an understanding of the genetic basis of human disease. To achieve this it will be essential to be able to characterize the phenotypic consequences of variation and alterations in individual genes. Data on the phenotypes of mouse strains are currently held in a number of different forms (detailed descriptions of mouse lines, first-line phenotyping data on novel mutations, data on the normal features of inbred lines) at many sites worldwide. For the most efficient use of these data sets, we have initiated a process to develop standards for the description of phenotypes (using ontologies) and file formats for the description of phenotyping protocols and phenotype data sets. This process is ongoing and needs to be supported by the wider mouse genetics and phenotyping communities to succeed. We invite interested parties to contact us as we develop this process further.

Original language	English
Pages (from-to)	157-163
Number of pages	7
Journal	Mammalian Genome
Volume	18
Issue number	3
DOIs	https://doi.org/10.1007/s00335-007-9004-x
State	Published - Mar 2007
Externally published	Yes

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Hancock, J. M., Adams, N. C., Aidinis, V., Blake, A., Blake, J. A., Bogue, M., Brown, S. D. M., Chesler, E., Davidson, D., Duran, C., Eppig, J. T., Gailus-Durner, V., Gates, H., Gkoutos, G. V., Greenaway, S., De Angelis, M. H., Kollias, G., Leblanc, S., Lee, K., ... Zouberakis, M. (2007). Integration of mouse phenome data resources. Mammalian Genome, 18(3), 157-163. https://doi.org/10.1007/s00335-007-9004-x

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abstract = "Understanding the functions encoded in the mouse genome will be central to an understanding of the genetic basis of human disease. To achieve this it will be essential to be able to characterize the phenotypic consequences of variation and alterations in individual genes. Data on the phenotypes of mouse strains are currently held in a number of different forms (detailed descriptions of mouse lines, first-line phenotyping data on novel mutations, data on the normal features of inbred lines) at many sites worldwide. For the most efficient use of these data sets, we have initiated a process to develop standards for the description of phenotypes (using ontologies) and file formats for the description of phenotyping protocols and phenotype data sets. This process is ongoing and needs to be supported by the wider mouse genetics and phenotyping communities to succeed. We invite interested parties to contact us as we develop this process further.",

author = "Hancock, {John M.} and Adams, {Niels C.} and Vassilis Aidinis and Andrew Blake and Blake, {Judith A.} and Molly Bogue and Brown, {Steve D.M.} and Elissa Chesler and Duncan Davidson and Christopher Duran and Eppig, {Janan T.} and Val{\'e}rie Gailus-Durner and Hilary Gates and Gkoutos, {Georgios V.} and Simon Greenaway and {De Angelis}, {Martin Hrab{\'e}} and George Kollias and Sophie Leblanc and Kirsty Lee and Christoph Lengger and Holger Maier and Mallon, {Ann Marie} and Hiroshi Masuya and Melvin, {David G.} and Werner M{\"u}ller and Helen Parkinson and Glenn Proctor and Eli Reuveni and Paul Schofield and Aadya Shukla and Cynthia Smith and Tetsuro Toyoda and Laurent Vasseur and Shigeharu Wakana and Alison Walling and Jacqui White and Joe Wood and Michalis Zouberakis",

year = "2007",

month = mar,

doi = "10.1007/s00335-007-9004-x",

language = "אנגלית",

volume = "18",

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Hancock, JM, Adams, NC, Aidinis, V, Blake, A, Blake, JA, Bogue, M, Brown, SDM, Chesler, E, Davidson, D, Duran, C, Eppig, JT, Gailus-Durner, V, Gates, H, Gkoutos, GV, Greenaway, S, De Angelis, MH, Kollias, G, Leblanc, S, Lee, K, Lengger, C, Maier, H, Mallon, AM, Masuya, H, Melvin, DG, Müller, W, Parkinson, H, Proctor, G, Reuveni, E, Schofield, P, Shukla, A, Smith, C, Toyoda, T, Vasseur, L, Wakana, S, Walling, A, White, J, Wood, J & Zouberakis, M 2007, 'Integration of mouse phenome data resources', Mammalian Genome, vol. 18, no. 3, pp. 157-163. https://doi.org/10.1007/s00335-007-9004-x

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AU - Hancock, John M.

AU - Adams, Niels C.

AU - Aidinis, Vassilis

AU - Blake, Andrew

AU - Blake, Judith A.

AU - Bogue, Molly

AU - Brown, Steve D.M.

AU - Chesler, Elissa

AU - Davidson, Duncan

AU - Duran, Christopher

AU - Eppig, Janan T.

AU - Gailus-Durner, Valérie

AU - Gates, Hilary

AU - Gkoutos, Georgios V.

AU - Greenaway, Simon

AU - De Angelis, Martin Hrabé

AU - Kollias, George

AU - Leblanc, Sophie

AU - Lee, Kirsty

AU - Lengger, Christoph

AU - Maier, Holger

AU - Mallon, Ann Marie

AU - Masuya, Hiroshi

AU - Melvin, David G.

AU - Müller, Werner

AU - Parkinson, Helen

AU - Proctor, Glenn

AU - Reuveni, Eli

AU - Schofield, Paul

AU - Shukla, Aadya

AU - Smith, Cynthia

AU - Toyoda, Tetsuro

AU - Vasseur, Laurent

AU - Wakana, Shigeharu

AU - Walling, Alison

AU - White, Jacqui

AU - Wood, Joe

AU - Zouberakis, Michalis

PY - 2007/3

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AB - Understanding the functions encoded in the mouse genome will be central to an understanding of the genetic basis of human disease. To achieve this it will be essential to be able to characterize the phenotypic consequences of variation and alterations in individual genes. Data on the phenotypes of mouse strains are currently held in a number of different forms (detailed descriptions of mouse lines, first-line phenotyping data on novel mutations, data on the normal features of inbred lines) at many sites worldwide. For the most efficient use of these data sets, we have initiated a process to develop standards for the description of phenotypes (using ontologies) and file formats for the description of phenotyping protocols and phenotype data sets. This process is ongoing and needs to be supported by the wider mouse genetics and phenotyping communities to succeed. We invite interested parties to contact us as we develop this process further.

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JO - Mammalian Genome

JF - Mammalian Genome

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ER -

Integration of mouse phenome data resources

Abstract

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