TY - GEN
T1 - Inhibitory effects of cobalt ions on the endothelial cell cycle. Implications for impairment of wound healing
AU - Peters, K.
AU - Scholz, A.
AU - Unger, R. E.
AU - Lubesder-Martellato, C.
AU - Stürzl, M.
AU - Kirkpatrick, C. J.
PY - 2004
Y1 - 2004
N2 - The effects of divalent cobalt ions on the inflammatory and proliferative response of human endothelial cells (EC) were investigated. The expression of pro-inflammatory and cell cycle-involved factors were also examined. Staining of the cell cycle-associated protein revealed a strong reduction of proliferative activity after Co2+-exposure. The results revealed that the decrease was due to a severe reduction of the S-phase population of the cell cycle.
AB - The effects of divalent cobalt ions on the inflammatory and proliferative response of human endothelial cells (EC) were investigated. The expression of pro-inflammatory and cell cycle-involved factors were also examined. Staining of the cell cycle-associated protein revealed a strong reduction of proliferative activity after Co2+-exposure. The results revealed that the decrease was due to a severe reduction of the S-phase population of the cell cycle.
UR - https://www.scopus.com/pages/publications/13844296564
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AN - SCOPUS:13844296564
SN - 1877040193
SN - 9781877040191
T3 - Transactions - 7th World Biomaterials Congress
SP - 1342
BT - Transactions - 7th World Biomaterials Congress
T2 - Transactions - 7th World Biomaterials Congress
Y2 - 17 May 2004 through 21 May 2004
ER -