Abstract
Background: Fibromyalgia syndrome (FMS) is a chronic disorder characterized by widespread musculoskeletal pain accompanied by various additional symptoms. The prevalence of FMS ranges between 2-8% of the population. The exact pathophysiology of the disease remains unknown, and under certain circumstances it is difficult for the physician to diagnose. Previous studies have shown a correlation between inflammatory biomarkers such as C-reactive protein (CRP) and FMS activity, suggesting that an inflammatory component may play a role in this disease pathogenesis. Objectives: To investigate the role of certain new inflammatory biomarkers in the diagnosis of patients with FMS. Methods: In this study data were collected from FMS patients who were admitted to Ziv Medical Center during the period 2013 to 2019 in an attempt to find a connection between inflammatory markers detectable by a traditional complete blood count (CBC) tests such as neutrophil-lymphocytes ratio (NLR), platelet-lymphocyte ratio (PLR), mean platelet value (MPV), red cell distribution width (RDW), and C-reactive protein (CRP) and FMS. Results: We found significantly higher CRP levels, MPV, and PLR and lower lymphocyte count in the FMS group compared to the control group. Conclusions: FMS has certain inflammatory components that may be useful in disease diagnosis.
Original language | English |
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Pages (from-to) | 801-804 |
Number of pages | 4 |
Journal | Israel Medical Association Journal |
Volume | 23 |
Issue number | 12 |
State | Published - Dec 2021 |
Bibliographical note
Publisher Copyright:© 2021 Israel Medical Association. All rights reserved.
Keywords
- C-reactive protein (CRP)
- Fibromyalgia syndrome (FMS)
- Mean platelet value (MPV)
- Neutrophil-lymphocyte ratio (NLR)
- Platelet-lymphocyte ratio (PLR) red cell distribution width (RDW)