Induction of apoptosis by apocarotenoids in B16 melanoma cells through ROS-mediated mitochondrial-dependent pathway

Keyphrases

• B16 Melanoma Cells 100%
• Reactive Oxygen Species 100%
• Apoptosis Induction 100%
• Mitochondrial Pathway 100%
• Apocarotenoids 100%
• Bixin 50%
• Norbixin 50%
• Anti-apoptotic Bcl-2 33%
• Gene Expression 16%
• Apoptosis 16%
• Pro-apoptotic 16%
• Anticancer Agents 16%
• Melanoma 16%
• Cell Morphology 16%
• Cell Viability 16%
• Morphological Changes 16%
• Concentration-dependent 16%
• Mitochondrial Dysfunction 16%
• Caspase-3 Activity 16%
• Reactive Oxygen Species Production 16%
• DNA Fragmentation 16%
• Hydrophobic Interaction 16%
• Death Pathway 16%
• Bcl-xL 16%
• Caspase-9 16%
• B16 Melanoma 16%
• Nuclear Condensation 16%
• Bixa Orellana 16%
• Molecular Docking Studies 16%
• Natural Food Colorant 16%
• Activated Caspases 16%
• B16 murine Melanoma 16%
• Microphthalmia-associated Transcription Factor 16%
• DNA Mitochondrial 16%
• Glutathione Activity 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Antiapoptotic 100%
• Reactive Oxygen Metabolite 100%
• Melanoma 100%
• Melanoma B16 100%
• Cell Viability 50%
• Anticarcinogen 50%
• Antiinfective Agent 50%
• Glutathione 50%
• Protein Bcl 2 50%
• Caspase 9 50%
• Microphthalmia Associated Transcription Factor 50%
• DNA Condensation 50%
• Bixa orellana 50%
• Caspase 3 50%