Abstract
We report a novel optical single-emitter-localization methodology that uses the phase induced by path length differences in a Mach-Zehnder interferometer to improve localization precision. Using information theory, we demonstrate that the localization capability of a modified Fourier domain signal generated by photon interference enables a more precise localization compared to a standard Gaussian intensity distribution of the corresponding point-spread function. The calculations were verified by numerical simulations and an exemplary experiment, where the centers of metal nanoparticles were localized to a precision of 3 nm.
| Original language | English |
|---|---|
| Pages (from-to) | 10430-10437 |
| Number of pages | 8 |
| Journal | Nanoscale |
| Volume | 7 |
| Issue number | 23 |
| DOIs | |
| State | Published - 21 Jun 2015 |
Bibliographical note
Publisher Copyright:© 2014 The Royal Society of Chemistry.
Funding
| Funders | Funder number |
|---|---|
| National Science Foundation | 1309041 |
| National Institute of Neurological Disorders and Stroke | R01NS034307 |