TY - GEN
T1 - Incorporation of flux balance analysis in pre-β-oxidation network to detect carnitine translocase in the cardiac cell in Homo sapiens
AU - Vijayaragahavan, Tarika
AU - Tagore, Somnath
PY - 2013
Y1 - 2013
N2 - Fats are immensely important for the survival of the human body. These are stored in the body in the form of fatty acids and reused whenever the body is unable to consume essential fats(at the time of exercise, fasting etc). In the human heart cell, the transport of certain fatty acids into the mitochondria is required to produce energy. This is done via a certain enzyme called Carnitine Translocase. This paper emphasizes on the simulation of the presence of Carnitine Translocase. Metabolic flux balance analysis was done to detect the presence of this enzyme, thus by preventing the accumulation of excess Fatty Acyl Carnitine that is known to give rise to various Cardiovascular diseases such as hypoglycemia, arrhythmia etc.
AB - Fats are immensely important for the survival of the human body. These are stored in the body in the form of fatty acids and reused whenever the body is unable to consume essential fats(at the time of exercise, fasting etc). In the human heart cell, the transport of certain fatty acids into the mitochondria is required to produce energy. This is done via a certain enzyme called Carnitine Translocase. This paper emphasizes on the simulation of the presence of Carnitine Translocase. Metabolic flux balance analysis was done to detect the presence of this enzyme, thus by preventing the accumulation of excess Fatty Acyl Carnitine that is known to give rise to various Cardiovascular diseases such as hypoglycemia, arrhythmia etc.
KW - CPT
KW - Carnitine Translocase
KW - Carnitine shuttle
KW - Fatty acids
KW - Flux Balance Analysis
KW - Malonyl-CoA
UR - http://www.scopus.com/inward/record.url?scp=84883158571&partnerID=8YFLogxK
U2 - 10.1109/AICERA-ICMiCR.2013.6576008
DO - 10.1109/AICERA-ICMiCR.2013.6576008
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AN - SCOPUS:84883158571
SN - 9781467351492
T3 - 2013 Annual International Conference on Emerging Research Areas, AICERA 2013 and 2013 International Conference on Microelectronics, Communications and Renewable Energy, ICMiCR 2013 - Proceedings
BT - 2013 Annual International Conference on Emerging Research Areas, AICERA 2013 and 2013 International Conference on Microelectronics, Communications and Renewable Energy, ICMiCR 2013 - Proceedings
T2 - 2013 Annual International Conference on Emerging Research Areas, AICERA 2013 and 2013 International Conference on Microelectronics, Communications and Renewable Energy, ICMiCR 2013
Y2 - 4 June 2013 through 6 June 2013
ER -