In vivo tumor detection using polarization and wavelength reflection characteristics of gold nanorods

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Abstract

This paper presents a novel concept involving sensing the back-reflected and absorbed light at two polarization states and at several wavelengths from gold nanorods (GNRs). While the GNRs are flowing in the bloodstream the reflected light has a high degree of polarization and only one resonance wavelength. When the GNRs are located in a tumor the reflected light has a low degree of polarization and two resonance wavelengths are detected. Such characteristics can assist in detecting a tumor in passive targeting and without labeling it.

Original languageEnglish
Pages (from-to)6292-6296
Number of pages5
JournalNano Letters
Volume13
Issue number12
DOIs
StatePublished - 11 Dec 2013

Keywords

  • GNR absorbance
  • GNR back-reflection
  • GNR spectra
  • Gold-nanorods (GNRs)
  • polarization
  • tumor detection

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