TY - JOUR
T1 - In vivo quantification of clot formation in extracorporeal circuits
AU - Gerrah, Rabin
AU - David, Omid
PY - 2013
Y1 - 2013
N2 - Clot formation is a common complication in extracorporeal circuits. In this paper we describe a novel method for clot formation analysis using image processing. We assembled a closed extracorporeal circuit and circulated blood at varying speeds. Blood filters were placed in downstream of the flow, and clotting agents were added to the circuit. Digital images of the filter were subsequently taken, and image analysis was applied to calculate the density of the clot. Our results show a significant correlation between the cumulative size of the clots, the density measure of the clot based on image analysis, and flow duration in the system.
AB - Clot formation is a common complication in extracorporeal circuits. In this paper we describe a novel method for clot formation analysis using image processing. We assembled a closed extracorporeal circuit and circulated blood at varying speeds. Blood filters were placed in downstream of the flow, and clotting agents were added to the circuit. Digital images of the filter were subsequently taken, and image analysis was applied to calculate the density of the clot. Our results show a significant correlation between the cumulative size of the clots, the density measure of the clot based on image analysis, and flow duration in the system.
KW - clot formation
KW - connected component labeling
KW - extracorporeal circuits
UR - http://www.scopus.com/inward/record.url?scp=84879522475&partnerID=8YFLogxK
U2 - 10.3233/978-1-61499-209-7-148
DO - 10.3233/978-1-61499-209-7-148
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 23400147
AN - SCOPUS:84879522475
SN - 0926-9630
VL - 184
SP - 148
EP - 150
JO - Studies in Health Technology and Informatics
JF - Studies in Health Technology and Informatics
ER -