In vivo minimally invasive interstitial multi-functional microendoscopy

Asaf Shahmoon, Shiran Aharon, Oded Kruchik, Martin Hohmann, Hamutal Slovin, Alexandre Douplik, Zeev Zalevsky

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Developing minimally invasive methodologies for imaging of internal organs is an emerging field in the biomedical examination research. This paper introduces a new multi-functional microendoscope device capable of imaging of internal organs with a minimal invasive intervention. In addition, the developed microendoscope can also be employed as a monitoring device for measuring local hemoglobin concentration in blood stream when administrated into a blood artery. The microendoscope device has a total external diameter of only 200â€...μm and can provide high imaging resolution capability of more than 5,000 pixels. The device can detect features with a spatial resolution of less than 1â€...μm. The microendoscope has been tested both in-vitro as well as in-vivo in rats presenting a promising and powerful tool as a high resolution and minimally invasive imaging facility suitable for previously unreachable clinical modalities.

Original languageEnglish
Article number1805
JournalScientific Reports
StatePublished - 2013

Bibliographical note

Funding Information:
The authors would like to acknowledge the financial support given to this research from NIH grant R21 5R21EB009138-02 entitled ‘‘Novel nano-pipette for imaging of deep cortical layers and deep brain structures’’. Zeev Zalevsky also gratefully acknowledges the Leon and Maria Taubenblatt Prize for Excellence in Medical Research for supporting his research activity.


Dive into the research topics of 'In vivo minimally invasive interstitial multi-functional microendoscopy'. Together they form a unique fingerprint.

Cite this