In Vitro and Mechanistic Studies of an Antiamyloidogenic Self-Assembled Cyclic d, l-α-Peptide Architecture

Keyphrases

• In Vitro Study 100%
• Mechanistic Studies 100%
• Anti-amyloid Treatment 100%
• NMR Spectroscopy 50%
• Transmission Electron Microscopy 50%
• Aggregation Behavior 50%
• Secondary Structure 50%
• Alzheimer 50%
• Cell Survival 50%
• Cross-reactivity 50%
• Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE) 50%
• Thioflavin T 50%
• Photoinduced 50%
• Misfolding 50%
• Immunoassay 50%
• Oligomer Distribution 50%
• In Vivo Model 50%
• Disassembling 50%
• Peptide Structure 50%
• Co-incubation 50%
• Toxic Oligomers 50%
• Amyloid Structure 50%
• Circular Dichroism Spectroscopy 50%
• Three-dimensional Features 50%
• Focused Library 50%
• Parallel Structure 50%
• Oligomeric State 50%
• Pheochromocytoma Cells 50%
• Lead Peptide 50%
• Survival Assay 50%

Chemistry

• Antiamyloidogenic 100%
• Mechanistic Study 100%
• Peptide 100%
• Toxic 37%
• Oligomer 37%
• NMR Spectroscopy 25%
• formation 25%
• Circular Dichroism 12%
• Transmission Electron Microscopy 12%
• SDS Polyacrylamide Gel Electrophoresis 12%
• Cell Viability 12%
• Secondary Structure 12%
• Immunoassay 12%

Biochemistry, Genetics and Molecular Biology

• Peptide 100%
• Amyloid Protein 28%
• Cross-Link 14%
• Nuclear Magnetic Resonance Spectroscopy 14%
• Conformation 14%
• Protein Secondary Structure 14%
• Protein Structure 14%
• Cell Survival 14%
• Cross Reaction 14%
• Thioflavin 14%
• Immunoassay 14%
• Polyacrylamide Gel Electrophoresis 14%
• Circular Dichroism 14%
• Rat 14%
• Transmission Electron Microscopy 14%