In search of clinical impact: Advanced monitoring technologies in daily heart failure care

Dean Nachman, Eldad Rahamim, Yotam Kolben, Bethlehem Mengesha, Gabby Elbaz-Greener, Offer Amir, Rabea Asleh

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations

Abstract

Despite significant advances in the management of heart failure (HF), further improvement in the outcome of this chronic and progressive disease is still considered a major unmet need. Recurrent hospitalizations due to decompensated HF frequently occur, resulting in increased morbidity and mortality rates. Past attempts at early detection of clinical deterioration were mainly based on monitoring of signs and symptoms of HF exacerbation, which have mostly given disappointing results. Extensive research of the pathophysiology of HF decompensation has indicated that hemodynamic alterations start days prior to clinical manifestation. Novel technologies aim to monitor these minute hemodynamic changes, allowing time for therapeutic interventions to prevent hemodynamic derangement and HF exacerbation. The latest noticeable advancements include assessment of lung fluid volume, wearable devices with integrated sensors, and microelectromechanical systems-based implantable devices for continuous measurement of cardiac filling pressures. This manuscript will review the rationale for monitoring HF patients and discuss previous and ongoing attempts to develop clinically meaningful monitoring devices to improve daily HF health care, with particular emphasis on the recent advances and clinical trials relevant to this evolving field.

Original languageEnglish
Article number4692
JournalJournal of Clinical Medicine
Volume10
Issue number20
DOIs
StatePublished - 13 Oct 2021

Bibliographical note

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Keywords

  • Heart failure
  • Novel technologies
  • Preventive medicine
  • Rehospital-ization
  • Remote patient monitoring
  • Telemedicine

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