@article{83051217e9fd429581e1b4bfdc08516c,
title = "Impaired anticipatory event-related potentials in schizophrenia",
abstract = "Deficits in anticipation are implicated across a variety of cognitive and emotional processes in schizophrenia. Although diminished anticipatory event-related potentials (ERPs) have been detected during tasks requiring motor response preparation in schizophrenia, no prior ERP study has examined non-motor-related anticipatory processes or used motivationally engaging stimuli. Thirty-four schizophrenia outpatients and 36 healthy controls completed a cued, reaction-time contingent picture viewing task to assess two types of anticipatory ERPs, one involving motor response preparation (Contingent Negative Variation [CNV]) and one not involving motor preparation (Stimulus Preceding Negativity [SPN]). The ERP paradigm included emotional and non-emotional pictures, and participants also completed trait anhedonia questionnaires. Patients and controls demonstrated similar patterns of reaction time and self-reported emotional responses to the pictures. However, patients demonstrated generally lower CNV and SPN across pleasant, neutral, and unpleasant picture conditions. Patients also reported lower anticipatory pleasure than controls on a trait questionnaire. Schizophrenia patients demonstrate diminished motor- and non-motor-related anticipatory processing, which may have wide-ranging adverse functional consequences.",
keywords = "Anticipation, Event-related potentials (ERP), Schizophrenia",
author = "Wynn, {Jonathan K.} and Horan, {William P.} and Kring, {Ann M.} and Simons, {Robert F.} and Green, {Michael F.}",
year = "2010",
month = aug,
doi = "10.1016/j.ijpsycho.2010.05.009",
language = "אנגלית",
volume = "77",
pages = "141--149",
journal = "International Journal of Psychophysiology",
issn = "0167-8760",
publisher = "Elsevier B.V.",
number = "2",
}