Immunization of mice against various strains of Pseudomonas aeruginosa by using Pseudomonas lectin vaccine

Dvora Sudakevitz, Nechama Gilboa-Garber

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The ability of Pseudomonas aeruginosa purified lectin vaccine to protect ICR mice against lethal infection caused by various serotypes of this bacterium was examined. Intraperitoneal injection of the lectin preparation was effective in full protection of the mice against the homologous strain. It was also effective in conferring from a partial to a full protection against most of the other virulent strains tested. The only strain which was still lethal for the immunized mice was one which produces exotoxin A but not lectins.

Original languageEnglish
Pages (from-to)313-315
Number of pages3
JournalFEMS Microbiology Letters
Volume43
Issue number3
DOIs
StatePublished - Sep 1987

Bibliographical note

Funding Information:
This work was supported by a research grant of the National Council for Research and Development.

Funding

This work was supported by a research grant of the National Council for Research and Development.

FundersFunder number
National Council for Research and Development

    Keywords

    • Immunization
    • Pseudomonas aeruginosa
    • Pseudomonas lectin
    • Vaccine

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