Imidazole and trifluoroethanol as efficient and mild reagents for destruction of excess di-tert-butyl dicarbonate [(BOC)2O]1

Y. Basel; A. Hassner

Imidazole and trifluoroethanol as efficient and mild reagents for destruction of excess di-tert-butyl dicarbonate [(BOC)₂O]¹

Y. Basel, A. Hassner

Department of Chemistry

Bar-Ilan University

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Mild and efficient procedures employing inexpensive reagents (imidazole or trifluoroethanol) for the removal of excess (BOC)₂O, usually used during NH or OH protection at room temperature, are described. The use of polymer-based DMAP with or without TFE was also found to be attractive.

Original language	English
Pages (from-to)	550-552
Number of pages	3
Journal	Synthesis
Issue number	4
State	Published - 2001

Keywords

(BOC)O excess
DMAP
Imidazole (Im)
PolyDMAP
Trifluoroethanol (TFE)

Cite this

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title = "Imidazole and trifluoroethanol as efficient and mild reagents for destruction of excess di-tert-butyl dicarbonate [(BOC)2O]1",

abstract = "Mild and efficient procedures employing inexpensive reagents (imidazole or trifluoroethanol) for the removal of excess (BOC)2O, usually used during NH or OH protection at room temperature, are described. The use of polymer-based DMAP with or without TFE was also found to be attractive.",

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author = "Y. Basel and A. Hassner",

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T1 - Imidazole and trifluoroethanol as efficient and mild reagents for destruction of excess di-tert-butyl dicarbonate [(BOC)2O]1

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AU - Hassner, A.

PY - 2001

Y1 - 2001

N2 - Mild and efficient procedures employing inexpensive reagents (imidazole or trifluoroethanol) for the removal of excess (BOC)2O, usually used during NH or OH protection at room temperature, are described. The use of polymer-based DMAP with or without TFE was also found to be attractive.

AB - Mild and efficient procedures employing inexpensive reagents (imidazole or trifluoroethanol) for the removal of excess (BOC)2O, usually used during NH or OH protection at room temperature, are described. The use of polymer-based DMAP with or without TFE was also found to be attractive.

KW - (BOC)O excess

KW - DMAP

KW - Imidazole (Im)

KW - PolyDMAP

KW - Trifluoroethanol (TFE)

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SN - 0039-7881

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JO - Synthesis

JF - Synthesis

IS - 4

ER -

Imidazole and trifluoroethanol as efficient and mild reagents for destruction of excess di-tert-butyl dicarbonate [(BOC)₂O]¹

Abstract

Keywords

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