Identifying Cognitive Mechanisms Targeted for Treatment Development in Schizophrenia: An Overview of the First Meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia Initiative

Cameron S. Carter, Deanna M. Barch, Robert W. Buchanan, Ed Bullmore, John H. Krystal, Jonathan Cohen, Mark Geyer, Michael Green, Keith H. Nuechterlein, Trevor Robbins, Steven Silverstein, Edward E. Smith, Milton Strauss, Til Wykes, Robert Heinssen

Research output: Contribution to journalReview articlepeer-review

162 Scopus citations

Abstract

This overview describes the generation and development of the ideas that led to the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) initiative. It also describes the organization, process, and products of the first meeting. The CNTRICS initiative involves a series of three conferences that will systematically address barriers to translating paradigms developed in the basic animal and human cognitive neuroscience fields for use in translational research aimed at developing novel treatments for cognitive impairments in schizophrenia. The articles in this special section report on the results of the first conference, which used a criterion-based consensus-building process to develop a set of cognitive constructs to be targeted for translation efforts.

Original languageEnglish
Pages (from-to)4-10
Number of pages7
JournalBiological Psychiatry
Volume64
Issue number1
DOIs
StatePublished - 1 Jul 2008
Externally publishedYes

Bibliographical note

Funding Information:
This article presents a summary of a conference supported by the National Institute of Mental Health (NIMH). The views expressed are those of the authors and do not necessarily reflect the official views of the NIMH, the National Institutes of Health, or any other branch of the U.S. Department of Health and Human Services.

Funding

This article presents a summary of a conference supported by the National Institute of Mental Health (NIMH). The views expressed are those of the authors and do not necessarily reflect the official views of the NIMH, the National Institutes of Health, or any other branch of the U.S. Department of Health and Human Services.

FundersFunder number
National Institute of Mental HealthR13MH078710
Medical Research CouncilG0001354

    Keywords

    • Cognitive neuroscience
    • schizophrenia
    • translational research
    • treatment development

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