Hypertension-misattributed kidney disease in African Americans

Karl L. Skorecki; Walter G. Wasser

doi:10.1038/ki.2012.369

Hypertension-misattributed kidney disease in African Americans

Karl L. Skorecki, Walter G. Wasser

Research output: Contribution to journal › Comment/debate

28 Scopus citations

Abstract

Lipkowitz et al. extend the African American Study of Kidney Disease and Hypertension to the level of genetic epidemiology, in a case-control study design. Analysis of genotypes at the APOL1 kidney disease risk region supports a paradigm shift in which genetic risk is proximate to both kidney disease and hypertension. The findings mandate urgency in clarifying mechanisms whereby APOL1 region risk variants interact with environmental triggers to cause progressive kidney disease accompanied by dangerous hypertension.

Original language	English
Pages (from-to)	6-9
Number of pages	4
Journal	Kidney International
Volume	83
Issue number	1
DOIs	https://doi.org/10.1038/ki.2012.369
State	Published - Jan 2013
Externally published	Yes

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Hypertension-misattributed kidney disease in African Americans

Abstract

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