Hydrogen/Deuterium Exchange Mass Spectrometry of Human Green Opsin Reveals a Conserved Pro-Pro Motif in Extracellular Loop 2 of Monostable Visual G Protein-Coupled Receptors

Keyphrases

• G Protein-coupled Receptor 100%
• Opsin 100%
• Cone Opsin 100%
• Hydrogen-deuterium Exchange Mass Spectrometry 100%
• Green Cone 100%
• Extracellular Loop 2 100%
• Hydrogen-deuterium Exchange 60%
• Transmembrane Helix 40%
• Chromophore 40%
• Rhodopsin 40%
• Active State 40%
• Retina 20%
• Conformational Change 20%
• Mass Spectrometry 20%
• Binding Site 20%
• Functional Assessment 20%
• Sequence Analysis 20%
• Light Activation 20%
• N-terminal Region 20%
• Solvent Accessibility 20%
• Glycosylation Site 20%
• Light Sensitive 20%
• Protein Components 20%
• Sequence Alignment 20%
• Inactive State 20%
• Structural Heterogeneity 20%
• Exchange-coupled 20%
• Biochemical Signals 20%
• Further Analysis 20%
• Deuterium Uptake 20%

Neuroscience

• Opsin 100%
• Mass Spectrometry 100%
• Cone Opsin 100%
• G Protein Coupled Receptor 100%
• Rhodopsin 40%
• Binding Site 20%
• Amino Terminal Sequence 20%
• Glycosylation 20%

Biochemistry, Genetics and Molecular Biology

• Hydrogen/Deuterium Exchange Mass Spectrometry 100%
• G Protein Coupled Receptor 100%
• Opsin 100%
• Hydrogen-Deuterium Exchange 42%
• Proteorhodopsin 28%
• Rhodopsin 28%
• N-Terminus 14%
• Conformational Change 14%
• Glycosylation 14%
• Mass Spectrometry 14%
• Binding Site 14%
• Sequence Alignment 14%